VEGF受体功能研究进展

被引:25
作者
倪效
燕敏
机构
[1] 上海交通大学医学院附属瑞金医院普外科上海消化外科研究所
关键词
血管内皮生长因子受体; 血管内皮生长因子; 信号通路;
D O I
暂无
中图分类号
Q46 [循环生理学];
学科分类号
摘要
血管内皮生长因子受体(VEGFR)调控心血管系统的发育。VEGFR1对于造血祖细胞的招募及单核巨噬细胞的迁移是必需的;VEGFR2、VEGFR3在调控血管及淋巴管内皮细胞的功能时发挥重要作用,而现在很多研究都聚焦于阻断VEGFR信号通路以达到阻断肿瘤血管生长的目的。
引用
收藏
页码:120 / 124
页数:5
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