肥胖的遗传基因与表观遗传修饰机制

被引：40

作者：

黄琪 ^{[1
]}

陈瑞 ^{[2
]}

梁凤霞 ^{[1
]}

机构：

[1] 湖北中医药大学针灸骨伤学院针灸治未病湖北省协同创新中心

[2] 华中科技大学同济医学院附属协和医院中西医结合科

来源：

华中科技大学学报(医学版) | 2018年 / 47卷 / 05期

关键词：

肥胖; 表观遗传学; 基因;

D O I：

暂无

中图分类号：

R589.2 [脂肪代谢障碍];

学科分类号：

100201 [内科学];

摘要：

<正>肥胖是以体脂过多为特征的多因素疾病,从1980年到2013年,成年人超重和肥胖的发生率提高了27.5%,儿童提高了47.1%[1]。以相同的增长速度,到2030年,全球将有21.6亿人超重,11.2亿人发展为肥胖,分别占世界成年人口的38%和20%[2]。因此,肥胖无疑已经成为全球面临的最重要的健康问题之一[3]。能量平衡异常是对发生肥胖最基本原因的认识[4]。无论是能量摄入增加还是消

引用

页码：644 / 647

页数：4

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