钙超载与心肌缺血再灌注损伤

被引:48
作者
徐新春
王文健
机构
[1] 上海市徐汇区中心医院!上海
[2] 上海医科大学附属华山医院中西医结合研究所!上海
关键词
calcium overload; ischemia- reperfusion injury; myocardium;
D O I
暂无
中图分类号
R363 [病理生理学];
学科分类号
100104 ;
摘要
The myocardial ischemia occurs when the blood supply of coronary artery cannot meet the energy needs of myocardium .Certain time and certain extentischmia can give rise to cell injury.Reperfusion is the essential measure to preventthe injury,but it was found recently that reperfusion could aggravate the injury.The pathogeny mechanism of ischemia- reperfusion(I- RI) injury remains incompletely elucidated.The thesis summarize the mechanism of I- RI only from calcium overload.
引用
收藏
页码:227 / 230
页数:4
相关论文
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Improvement of ischemic myocardial dysfunction by nisoldipine[J] . Kooichi Saida,Masaomi Umeda,Akemi Itakura.Cardiovascular Drugs and Therapy . 1994 (2)
[2]   NA+/H+ EXCHANGE AND ITS INHIBITION IN CARDIAC ISCHEMIA AND REPERFUSION [J].
SCHOLZ, W ;
ALBUS, U .
BASIC RESEARCH IN CARDIOLOGY, 1993, 88 (05) :443-455
[3]  
Kinetics of calcium accumulation in acute myocardial ischemic injury. Shen A C, Jennings R B. American Journal of Pathology . 1972