Fatty liver,carotid disease and gallstones:A study of age-related associations

被引：10

作者：

Amedeo Lonardo

Silvia Lombardini

Federica Scaglioni

Stefano Ballestri

Anna Maria Verrone

Marco Bertolotti

Lucia Carulli

Dorval Ganazzi

Nicola Carulli

Paola Loria

机构：

[1] University of Modena and Reggio Emilia-Azienda USL Department of Internal Medicine Metabolism Endocrinology and Geriatrics Ospedale di Baggiovara Via Giardini Modena 41100 Italy

[2] University of Modena and Reggio Emilia-Azienda USL Department of Internal Medicine Metabolism Endocrinology and Geriatrics Ospedale di Baggiovara Via Giardini Modena 41100 Italy

来源：

World Journal of Gastroenterology | 2006年 / 36期

关键词：

Atherosclerosis; Carotid; Gallstones; Intima-media thickening; Fatty liver;

D O I：

暂无

中图分类号：

R575.5 [肝代谢障碍]; R575.6 [胆囊疾病];

学科分类号：

1002 ; 100201 ;

摘要：

AIM: To evaluate carotid intima-media thickening (IMT) and plaques, gallstone disease (GD) and fatty liver (FL) as a function of age. METHODS: In 449 subjects, FL and carotid disease were assessed ultrasonographically. In a subgroup of 65/449 patients with non-alcoholic fatty liver disease (NAFLD), carotid disease, GD and associated factors were determined. RESULTS: FL of unspecified etiology was more common in younger and GD in older individuals. FL subjects had an increased prevalence of IMT and a decreased prevalence of plaques and manifested carotid disease earlier. Plaques were more common in subjects with GD. Age was an independent predictor of carotid disease outcome and FL was a protective factor for plaques. In NAFLD, there was an inverse correlation between body weight and age and the latter independently predicted carotid findings. CONCLUSION: Cardiovascular risk in patients with FL and NAFLD needs to be assessed as a function of age and body weight.

引用

页码：5826 / 5833

页数：8

共 3 条

[1]

Epidemiology and risk factors for gallstone disease: Has the paradigm changed in the 21st century?[J] . Eldon A. Shaffer.Current Gastroenterology Reports . 2005 (2)

[2]

Non-Organ-Specific Autoantibodies in Nonalcoholic Fatty Liver Disease: Prevalence and Correlates[J] . Paola Loria,Amedeo Lonardo,Francesca Leonardi,Cristina Fontana,Lucia Carulli,Anna Maria Verrone,Andrea Borsatti,Marco Bertolotti,Fabio Cassani,Alberto Bagni,Paolo Muratori,Dorval Ganazzi,Francesco B. Bianchi,Nicola Carulli.Digestive Diseases and Sciences . 2003 (11)

[3]

Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man[J] . D. R. Matthews,J. P. Hosker,A. S. Rudenski,B. A. Naylor,D. F. Treacher,R. C. Turner.Diabetologia . 1985 (7)

← 1 →