丹参酮ⅡA磺酸钠对冠心病心绞痛及血液流变学疗效观察

被引:21
作者
左玉姣
李颖庆
王刚
机构
[1] 南华大学附属第一医院心内科
关键词
丹参酮ⅡA磺酸钠注射液; 冠心病; 心肌缺血; 血液流变学;
D O I
10.13241/j.cnki.pmb.2007.05.030
中图分类号
R259 [现代医学内科疾病];
学科分类号
100506 ;
摘要
目的:观察丹参酮ⅡA磺酸钠对冠心病心肌缺血的有效性及血液流变学的影响。方法:将50例冠心病患者随机分为治疗组(26例)与对照组(24例)。对照组常规应用硝酸异山梨酯与阿司匹林等。前者在常规治疗基础上加用丹参酮ⅡA碘酸纳注射液60mg(1次/天)。每例于治疗开始前与结束后,进行血液流变学与心电图(ECG)检测。结果:两组心肌缺血症状治疗前后均有改善。与对照组相比,治疗组的效果更为显著(P均<0.05)。治疗组血液流变学指标:低切变率下全血黏度、高切变率下全血黏度、纤维蛋白原(Fbg)、血浆D-二聚体(DD)均显著下降(P<0.05)。其改善血液流变学指标的疗效优于对照组(P<0.05)。结论:丹参酮ⅡA磺酸钠可改善血液流变性作用,是治疗冠心病心肌缺血的一种有效的药物。
引用
收藏
页码:732 / 734
页数:3
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