冠心病患者血清FKN、MMP-9及MCP-1的水平变化附视频

被引：8

作者：

葛慧娟

庄晓赛

宁彬

机构：

[1] 阜阳市人民医院心血管内科

来源：

中国循证心血管医学杂志 | 2016年 / 03期

关键词：

冠心病; 不规则趋化因子; 基质金属蛋白酶9; 单核细胞趋化蛋白1;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

摘要：

目的观察冠心病患者血清不规则趋化因子（FKN）、基质金属蛋白酶9（MMP-9）以及单核细胞趋化蛋白1（MCP-1）的水平变化。方法选择2014年6月10月在阜阳市人民医院心血管内科住院的冠心病患者共144例,男性74例,女性70例,平均年龄（64.9±10.1）岁。其中稳定型心绞痛（SAP）组45例,不稳定型心绞痛（UAP）组55例,急性心肌梗死（AMI）组44例。另选取同期本院健康体检者50例作为对照组。采用ELISA法检测血清FKN、MMP-9以及MCP-1水平。结果与对照组比较,SAP组、UAP组及AMI组的FKN、MMP-9、MCP-1水平明显增高,差异有统计学意义（P均<0.05）;与SAP组比较,UAP组和AMI组的FKN、MMP-9、MCP-1水平明显升高,差异有统计学意义（P均<0.05）;与UAP组比较,AMI组上述三项因子水平均明显增高,差异有统计学意义（P均<0.05）。结论血清FKN、MMP-9以及MCP-1水平在冠心病患者中明显升高,有助于监测冠心病严重程度。

引用

页码：349 / 351

页数：3

共 17 条

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