阿那白滞素在风湿性关节炎疾病中的临床应用

被引：8

作者：

杨军

何庭艳

机构：

[1] 深圳市儿童医院肾脏免疫科

来源：

中华实用儿科临床杂志 | 2013年 / 28卷 / 09期

关键词：

风湿性关节炎; 阿那白滞素; 幼年特发性关节炎; 依那西普;

D O I：

暂无

中图分类号：

R593 [免疫性疾病];

学科分类号：

100201 [内科学];

摘要：

IL-1在关节炎疾病的软骨及骨组织破坏中发挥重要作用。人重组IL-1受体拮抗剂阿那白滞素可抑制IL-1活性, 为治疗此类疾病提供了新的选择。现主要论述阿那白滞素在类风湿性关节炎(RA)和幼年特发性关节炎(JIA)疾病中应用的有效性及安全性。阿那白滞素可改善RA或全身型JIA患者的临床症状, 并不增加严重不良反应的风险。

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