不同频率重复经颅磁刺激对阿尔茨海默病患者认知功能的影响

被引：48

作者：

吴越

徐文炜

刘晓伟

武曙燕

机构：

[1] 江苏省无锡市精神卫生中心

来源：

实用医学杂志 | 2015年 / 31卷 / 10期

关键词：

阿尔茨海默病; 重复经颅磁刺激; 认知功能;

D O I：

暂无

中图分类号：

R749.16 [];

学科分类号：

摘要：

目的:探讨不同频率重复经颅磁刺激(r TMS)对轻中度阿尔茨海默病(AD)患者认知功能的影响。方法:82例轻中度AD患者,随机分为高频组、低频组和对照组,3组患者分别给予20、1 Hz和伪刺激,疗程为4周。治疗前后分别采用阿尔茨海默病评定量表认知分量表(ADAS-Cog)、事件相关电位及脑电图检测进行疗效评定。结果:与治疗前相比,治疗4周末高频组和低频组ADAS-Cog总分、语言因子分、记忆因子分明显减低、事件相关电位及脑电图指标明显改善,对照组各评估指标较治疗前差异无显著性。组间比较,高频组疗效优于低频组。结论:r TMS可改善AD患者的认知功能,高频刺激的效果更佳。

引用

页码：1624 / 1627

页数：4

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