CD11/CD18在脑缺血再灌注损伤中的作用

被引:4
作者
夏斌
邵福源
机构
[1] 第二军医大学长征医院神经科
关键词
粘附分子; CD11; CD18; 脑缺血; 再灌注;
D O I
暂无
中图分类号
R364 [病理过程];
学科分类号
100104 ;
摘要
粘附分子CD11 CD18是在白细胞上表达的糖蛋白 ,缺血 再灌注损伤时的作用是介导白细胞与内皮细胞的粘附及渗出到缺血组织 ,缺血性卒中患者和脑缺血动物模型中均发现其表达升高。通过降低CD11 CD18可以减少脑梗死的体积和白细胞在缺血组织中的数量 ,有望成为治疗缺血性卒中的一种方法。
引用
收藏
页码:134 / 136
页数:3
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