肠道菌群与脑-肠轴功能相互影响的研究进展

被引：63

作者：

张璐

刘懿萱

段丽萍

机构：

[1] 北京大学第三医院消化科

来源：

胃肠病学 | 2014年 / 19卷 / 09期

关键词：

肠道菌群; 脑-肠轴; 肠黏膜; 迷走神经;

D O I：

暂无

中图分类号：

R333 [消化与吸收生理];

学科分类号：

100123 [人体微生态学];

摘要：

人体肠道内的菌群参与了许多生理功能的维持和疾病的发生。作为大脑和胃肠道功能相互调节的重要桥梁,脑-肠轴功能的正常发挥是肠道菌群维持稳定的条件。脑-肠轴紊乱可激活肠黏膜免疫,对肠道菌群产生影响,使菌群结构发生改变。反之,肠道菌群结构改变亦会影响神经系统发育,导致脑-肠轴功能紊乱,其中迷走神经和血清代谢物质在脑-肠轴功能的调节中发挥重要作用。本文就肠道菌群与脑-肠轴功能相互影响的研究进展作一综述。

引用

收藏

页码：563 / 565

页数：3

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