骨关节炎与软骨下骨研究进展

被引：39

作者：

常亮

秦江辉

史冬泉

蒋青

机构：

[1] 南京鼓楼医院运动医学与成人重建外科

来源：

中华骨与关节外科杂志 | 2019年 / 12卷 / 10期

关键词：

骨关节炎; 软骨下骨;

D O I：

暂无

中图分类号：

R684.3 [关节炎];

学科分类号：

100220 [骨科学];

摘要：

骨关节炎(OA)是以关节软骨退变、软骨下骨硬化为主要特征的关节退行性疾病。近年来的研究发现,软骨下骨组织结构及其力学性能的改变是OA早期的重要病理进程之一。因此,明确软骨下骨在OA过程中的病理性改变及其对OA进程的影响,可以更全面地了解OA的发病机制,并为OA的治疗提供新视角。本文针对近年来关于软骨下骨与OA进程关系、软骨下骨损伤机制及以软骨下骨为靶点的治疗研究进行综述,为后续基础研究及临床转化工作提供帮助。

引用

页码：827 / 832

页数：6

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