血清甘油三酯变化在急性缺血性脑卒中的临床意义

被引：2

作者：

罗传松 ^{[1
]}

资文杰 ^{[2
]}

陈自光 ^{[1
]}

赵睿 ^{[1
]}

唐云 ^{[1
]}

机构：

[1] 重庆市梁平县人民医院

[2] 第三军医大学新桥医院

来源：

现代生物医学进展 | 2012年 / 12卷 / 33期

关键词：

甘油三酯; 急性缺血性脑卒中; 预后;

D O I：

10.13241/j.cnki.pmb.2012.33.043

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

摘要：

目的:探讨血清甘油三酯(TG)与急性缺血性脑卒中(AIS)早期预测之间的相关性。方法:我们收集了736例AIS患者。依据TG水平将患者分为5组。参照美国国立卫生研究院(为什么不参照我国的标准)卒中量表(NIHSS),将早期神经功能恶化(END)设定为≥4分,将新发症状开始一周后的早期临床改善(ECI)定为降低4分或以上。将各组内的END、ECI患者及两者都不是的患者进行比较。结果:高TG和低TG组患者发生END的风险显著高于正常组。高TG、低TG组以及临界组患者发生ECI的百分率显著低于正常组。多元回归分析显示高TG、低TG组以及临界组患者在END中的or值显著高于正常低值组(50-100 mg/dl)。AIS患者的甘油三酯(TG)水平与预后不良呈非线性的J型相关,与良好预后呈反J形相关。结论:在AIS的早期高TG和低TG都是预后不良的危险因素。

引用

页码：6499 / 6502+6514 +6514

页数：5

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