胃癌及癌前病变组织三叶因子3表达的相关性研究

被引:3
作者
黄亚平
雷琳
朱庆茹
机构
[1] 湖北省襄樊市中心医院
关键词
肠三叶因子; 胃癌; 表达;
D O I
10.16121/j.cnki.cn45-1347/r.2009.06.110
中图分类号
R735.2 [胃肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
目的检测三叶因子3(TFF3)在胃癌前病变及胃癌的表达,探讨TFF3的表达与胃癌发生、发展的关系。方法收集慢性浅表性胃炎(CSG),慢性萎缩性胃炎伴中、重度肠上皮化生(IM),慢性萎缩性胃炎伴中重度不典型增生(Dys)患者各30例,胃癌(GC)患者40例采用SP免疫组化法检测TFF3蛋白的表达。结果CSG、IM、Dys、GC组织中TFF3表达呈逐渐增强趋势,差异具有统计学意义(P<0.05)。结论TFF3表达在胃癌发生、发展过程中起一定作用。
引用
收藏
页码:854 / 856
页数:3
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