载脂蛋白E等位基因频率的种族差异——中国人群与西方人群的比较

被引:13
作者
陈保生
乔家治
乔彩莲
郭夏玲
樊廷兴
祝珍英
崔洪亮
徐宁生
孟庆玲
赵树林
机构
[1] 中国医学科学院基础医学研究所,河南商邱市第一人民医院,河南商邱市公费医疗医院,北京医科大学第一附属医院,河南商邱市公费医疗医院,河南商邱市公费医疗医院,河南商邱市第一人民医院,北京医科大学第一附属医院,北京医科大学第一附属医院,河南通许县卫生防疫站北京
关键词
载脂蛋白E; 等位基因; 表型分布;
D O I
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中图分类号
学科分类号
摘要
对507例中国人载脂蛋白E(apoE)表型及其等位基因频率进行分析,并比较东、西方民族间的异同。结果表明,中国人群apoE3/3表型分布及其等位基因ε3的频率与东方民族(日本)基本一致,但明显高于西方人群。中国人群的apoE3/4表型分布频率不仅低于西方人群,而且也低于东方其它民族。其它表型的分布频率在人群间无明显差异.可以认为apoE的表型分布及其等位基因频率在中国人群与西方人群之间存在着种族差异性。
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页码:397 / 401
页数:5
相关论文
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