骨髓源性血管内皮前体细胞与出生后生理性和病理性血管形成

被引：3

作者：

郑玮

杨向红

机构：

[1] 中国医科大学实验病理研究室,中国医科大学实验病理研究室辽宁沈阳,辽宁沈阳

来源：

中国病理生理杂志 | 2004年 / 09期

关键词：

骨髓; 内皮前体细胞; 新生血管化,病理性; 新生血管化,生理性;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100104 ;

摘要：

Endothelial progenitor cells (EPCs) exist in bone marrow, umbilical cord blood and peripheral blood of adult mammals, including humans. Furthermore, the discovery of EPCs has led to the notion of adult vasculogenesis, in which bone marrow (BM)-derived EPCs home to and incorporate into sites of new blood vessel formation, where they differentiate into endothelial cells, which is consistent with postnatal vasculogenesis. It has become apparent that circulating BM-derived EPCs are involved in promoting physiologic and pathologic neovascularization, such as wound healing and tumor growth. They are of great clinical importance in pro- or anti-angiogenic therapies. [

引用

页码：198 / 202

页数：5

共 31 条

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