糖皮质激素性骨质疏松症的研究进展

被引:10
作者
贺茂林
肖增明
机构
[1] 广西医科大学第一附属医院脊柱骨病科
关键词
糖皮质激素性骨质疏松症; 骨矿密度; 治疗;
D O I
暂无
中图分类号
R580 [];
学科分类号
摘要
糖皮质激素应用范围广泛且往往长期使用,它的主要副作用就是导致骨质疏松症并增加骨折风险。并非大剂量应用糖皮质激素才会导致骨质疏松。老年人及开始糖皮质激素治疗之前即存在骨矿密度低的患者,骨量丢失更加明显,更易导致骨折的发生。除了应用糖皮质激素以外,还有很多因素会导致骨量丢失,如:基础疾病、营养不良、维生素D缺乏、性腺发育不全及低体重等。本综述说明了糖皮质激素性骨质疏松症的发病率、高危人群、发病机制以及如何对其进行预防和治疗。目前预防糖皮质激素性骨质疏松症主要依赖于钙剂和维生素D的补充,充足的蛋白质摄取,定期的体育锻炼。一些新的治疗方法如双膦酸盐和甲状旁腺素的应用给糖皮质激素性骨质疏松症的治疗带来了希望。尽管我们的治疗和预防策略已有长足进步,我们还需要对它进行进一步的补充。
引用
收藏
页码:466 / 470+450 +450
页数:6
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