谷氨酸单钠对新生期大鼠下丘脑内侧基底部神经元的神经毒性作用

被引：9

作者：

吕永利

赵书芬

吕集

车春明

机构：

[1] 中国医科大学解剖学教研室

[2] 中国医科大学基础医学部生理学教研室

[3] 通化市卫生学校

[4] 西安市卫生学校

来源：

中国医科大学学报 | 1992年 / 04期

关键词：

谷氨酸单钠; 下丘脑弓状核; 下丘脑腹内侧核;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Monosodium glutamate (MSG) was injected into the skin of 12 new born rats (2mg/gm. one time/every second day, total 4 times). The neurodegenerative effect has been observed in the 5th, 9th and 12th week after the administration of MSG. Results showed that the degenerative neurons damaged by MSG were located in the hypothalamic arcuate nucleus and the hypothalamic ventromedial nucleus, but not in the hypothalamic dorsomedial nucleus. The neurodegenerative effct may be strengthened as the prolongation of the time and the increase of the dosage of SMG.

引用

页码：246 / 249

页数：4