肝癌术后TACE的抗复发作用

被引：7

作者：

吴晓健

罗放

王济明

涂经楷

机构：

[1] 重庆医科大学附属第一医院肝胆外科

来源：

激光杂志 | 2011年 / 32卷 / 04期

关键词：

肝细胞性肝癌; 术后; 复发;

D O I：

暂无

中图分类号：

R735.7 [肝肿瘤];

学科分类号：

100214 ;

摘要：

目的:从临床角度发现影响肝癌术后复发的原因,预防性TACE在延缓肝癌手术后复发中的作用。方法:从1999年2月到2006年2月,连续性收治326例肝癌患者,所有患者均接受了肝癌切除术。将可能影响原发性肝癌术后复发的观察指标包括性别、年龄、术前AFP、有无癌栓、手术切缘、手术前肿瘤是否破裂、肿瘤大小、肿瘤有无子灶、肿瘤包膜情况、手术后有无行预防性TACE等,用Cox模型分析各因素与复发时间之间的关系。结果:年龄小、有癌栓、手术前肿瘤有破裂、肿瘤体积大和肿瘤周围有子灶等因素使肝癌手术后复发时间提前,保证较大手术切缘距离和手术后行预防性TACE可延缓肝癌手术后复发。结论:对于存在术后复发高危倾向的患者,在术前、术中及术后采取相应措施,可有效提高术后无瘤生存率、延长生存时间。术后施行TACE,可能对具有早期复发倾向的肝癌患者具有作用。

引用

页码：58 / 60

页数：3

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