多囊卵巢综合征发病机制的研究进展

被引：15

作者：

赵晓苗

李扬志

杨冬梓

谢梅青

机构：

[1] 中山大学附属第二医院妇产科

来源：

中华妇产科杂志 | 2008年 / 02期

关键词：

D O I：

暂无

中图分类号：

R686 [筋腱、韧带、滑囊疾病及损伤];

学科分类号：

100220 [骨科学];

摘要：

<正> 多囊卵巢综合征(polycystic ovarian syndrome,PCOS)是一种影响生育年龄妇女的极为常见而复杂的内分泌紊乱性疾病,其复杂性在于症状的高度异质性和病因未知。由于有较强的家族聚集现象,越来越多的证据支持 PCOS 的遗传学病因;然而临床表现的高度异质性显示,绝大部分 PCOS 不可能受单一因素的影响,可能还受到环境因素的影响。根据来自动物模型的实验结果和人类临床证据,学者们又提出,PCOS 是起源于青春期前的一个连续的过程,这一发育过程中,遗传因素与环境因素的相互作用可能改变成年后

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