抗痛风新药非布司他的临床研究进展

被引:48
作者
刘玉艳
李阅东
唐建飞
沈如杰
姚成娥
机构
[1] 杭州朱养心药业有限公司
关键词
非布司他; 别嘌醇; 痛风; 高尿酸血症; 临床研究;
D O I
暂无
中图分类号
R98 [各科药物];
学科分类号
100705 [微生物与生化药学];
摘要
非布司他(febuxostat)为选择性黄嘌呤氧化酶抑制剂,是一种治疗痛风的新药。临床研究表明非布司他在治疗高尿酸血症及其引起的痛风方面具有良好的疗效及安全性。与别嘌醇相比,非布司他可快速降低血尿酸水平,尤其对于存在轻中度肾功能不全的患者无需调整剂量,且无明显不良反应。文中就非布司他国外的临床研究进行了综述。
引用
收藏
页码:1103 / 1106+1114 +1114
页数:5
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