远端胃癌腹腔镜手术对比传统开腹手术近期疗效的Meta分析

被引：26

作者：

黄昌明 ^{[1
]}

杨娜 ^{[1
]}

林涛 ^{[2
]}

郑朝辉 ^{[1
]}

李平 ^{[1
]}

谢建伟 ^{[1
]}

林碧娟 ^{[1
]}

卢辉山 ^{[1
]}

机构：

[1] 福建医科大学附属协和医院肿瘤外科

[2] 福建医科大学流行病与统计学系

来源：

中华肿瘤防治杂志 | 2011年 / 18卷 / 05期

关键词：

胃肿瘤; 腹腔镜手术; 胃切除术; Meta分析;

D O I：

10.16073/j.cnki.cjcpt.2011.05.012

中图分类号：

R735.2 [胃肿瘤];

学科分类号：

100112 [医学生物化学与分子生物学];

摘要：

目的:对比分析腹腔镜早期远端胃癌手术与传统开腹手术的近期疗效。方法:检索2000-01-2008-12发表的有关腹腔镜手术与传统开腹手术治疗早期远端胃癌近期疗效的文献。按筛选标准,共有14篇入选。由3名作者分别独立地对入选研究的有关试验设计、研究对象特征和研究结果等内容进行摘录,并用RevMan 5.0软件进行统计分析。结果:全体研究样本量合计1 394例早期胃癌,Meta分析结果显示,腹腔镜早期远端胃癌手术对比传统开腹手术:手术时间延长49.85 min〔加权均数差(WMD)49.85,95%可信区间(CI)32.02～67.68,P<0.05〕,但术中出血量减少145.50 mL(P<0.05),术后要求镇痛药的次数减少1.22次(P=0.01),术后第1次排气天数缩短0.57 d(P<0.05),术后第1次进食天数缩短0.88 d(P<0.05),术后住院天数缩短4.76 d(P<0.05),而且术后并发症发生率低,两者差异均有统计学意义,P<0.05;术后死亡率相当,差异无统计学意义,P=0.74。结论:腹腔镜早期远端胃癌手术对比传统开腹手术,虽然手术时间延长,但在手术创伤、术后恢复和术后并发症等方面具有明显的微创优势,是安全可行的。

引用

页码：355 / 360

页数：6

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