茵陈蒿汤护肝作用研究进展

被引：34

作者：

朱世敏 ^{[1
]}

唐志鹏 ^{[2
]}

机构：

[1] 上海中医药大学教学实验中心

[2] 上海中医药大学脾胃病研究所,上海中医药大学附属龙华医院消化内科

来源：

上海中医药杂志 | 2008年 / 02期

关键词：

茵陈蒿汤; 肝损伤; 肝纤维化; 综述;

D O I：

暂无

中图分类号：

R285 [中药药理学];

学科分类号：

100806 [中药药理学];

摘要：

茵陈蒿汤是临床上治疗肝病的有效方剂。茵陈蒿汤及其有效成分包括乙醇提取物、6,7-二甲氧基香豆素、茵陈二炔酮、茵陈炔、蒽醌类化合物和京尼平,能抑制核因子κB激活,减少炎症细胞因子产生和氧化应激,减轻肝细胞损伤和凋亡,抑制肝星状细胞激活和增殖,促进肝星状细胞凋亡,减少肝组织细胞外基质沉积,因而具有较显著的抗肝损伤和抗肝纤维化作用,为其临床应用和试验研究提供了科学依据。

引用

收藏

页码：73 / 75

页数：3

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