急性冠脉综合征患者血浆脑钠肽和C-反应蛋白的变化

被引：2

作者：

丁嵩

何奔

卜军

刘建平

宋玮

杜勇平

金叔宣

沈节艳

孙瑜

沈珑

机构：

[1] 上海交通大学医学院仁济医院心内科

来源：

上海交通大学学报(医学版) | 2006年 / 03期

关键词：

脑钠肽; C-反应蛋白; 急性冠脉综合征;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

1002 ; 100201 ;

摘要：

目的探讨急性冠脉综合征(ACS)患者血浆脑钠肽(BNP)和C-反应蛋白(CRP)的变化及其临床意义。方法采用荧光免疫抗原抗体结合方法,37例稳定型心绞痛(SAP)患者入院后第2天清晨及123例ACS患者症状发作后平均(35.71±19.49)h的血浆BNP水平;采用ELISA法测定患者入院第2日清晨血浆CRP水平。测定以63例冠脉造影正常、心功能正常者,作为对照。结果ACS患者血浆BNP和CRP水平明显升高。血浆BNP水平ACS组分别高于SAP组及对照组(P均<0.0001)。CRP水平ACS组分别高于SAP组及对照组(P均<0.001)。ACS组血浆BNP水平和CRP水平呈正相关(r=0.41813,P<0.0001)。结论ACS患者血浆BNP和CRP水平明显升高,提示二者在ACS的发病机制中起重要作用。

引用

页码：241 / 243

页数：3

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