不同左室射血分数等级冠心病患者接受冠状动脉介入治疗的预后分析

被引:8
作者
金彦彦 [1 ]
马长生 [2 ]
康俊萍 [2 ]
聂绍平 [2 ]
张崟 [2 ]
吕强 [2 ]
刘晓惠 [2 ]
胡荣 [2 ]
机构
[1] 首都医科大学附属安贞医院抢救中心
[2] 首都医科大学附属安贞医院心内科二病房
关键词
冠心病; 经皮冠状动脉介入治疗; 射血分数; 预后;
D O I
10.13201/j.issn.1001-1439.2012.01.012
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
目的:探讨不同心功能状态的冠心病患者接受冠状动脉介入(PCI)治疗的预后情况。方法:连续入选接受PCI治疗的2 234例患者,至少随访1年以上。按照LVEF分为:A组,LVEF≤40%(106例);B组,LVEF 41%~49%(205例);C组,LVEF≥50%(1 923例)。比较各组院内、长期死亡及主要不良心脑血管事件(MACCE)的发生率。结果:A、B、C组院内死亡率分别为2.8%、0.5%、0.2%,P<0.01;长期死亡率分别为5.7%、4.4%、1.6%,P<0.01。A、B、C组院内MACCE率为5.7%、2.0%、1.0%,P<0.01;长期MACCE率为18.8%、11.6%、11.7%,P<0.05。COX多因素回归示:A组患者长期死亡风险是C组患者的3.646倍(RR3.646,95%CI1.517~8.762);B组患者长期死亡风险是C组患者的2.184倍(RR2.184,95%CI 1.321~5.684)。结论:LVEF≤40%患者院内及长期死亡率和MACCE发生率仍明显高于LVEF>41%患者。
引用
收藏
页码:34 / 37
页数:4
相关论文
共 14 条
[1]  
Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysis[J] . Kevin C Allman,Leslee J Shaw,Rory Hachamovitch,James E Udelson. &nbspJournal of the American College of Cardiology . 2002 (7)
[2]  
Predictors of outcome in patients with acute cor-onary syndromes without persistent ST-segment ele-vation. BOERSMA E,PIEPER K S,STEVERBERG E W,et al. Circulation . 2000
[3]  
Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysis. Allman K C,Shaw L J,Hachamovitch R,et al. Journal of the American College of Cardiology . 2002
[4]  
Comparison of effectiveness of coronary artery bypass grafting versus percutaneous coronary intervention in patients with ischemic cardiomyopathy. Buszman P,Szkrobka I,Gruszka A,et al. The American Journal of Cardiology . 2007
[5]  
Revascularization in heart failure:coronary by-pass or percutaneous coronary intervention. Pusca SV,Puskas JD. Heart Fail Clin . 2007
[6]  
Heart failure with preservedleft ven-tricular systolic function among patients with non-ST-segmentelevation acute coronary syndromes. Bennett KM,Hernandez AF. The American Journal of Cardiology . 2007
[7]  
Renal function and risk stratification in acute coronary syndromes. Wison S,Foo K,Cunningham J,Cooper Jet al. The American Journal of Cardiology . 2003
[8]  
The effects of simvastatin on the incidence of heart failure in patients with coronary heart disease. Kjekshus J,Pedersen TR,Olsson AG,et al. Journal of Cardiology . 1997
[9]   Revascularization for patients with severe coronary artery disease and left ventricular dysfunction [J].
Ghose T. ;
Thompson R.C. .
Current Cardiology Reports, 2006, 8 (4) :255-260
[10]  
Improved survival for stenting vs.balloon angio-plasty for the treatment of coronary artery disease inpatients with ischemic left ventricular dysfunction. LIPINSKI M J,MARTIN R E,COWLEY M J,etal. Catheterization and Cardiovascular Interventions . 2005