人参皂苷对HPA轴作用的研究进展

被引：15

作者：

李慧 ^{[1
]}

刘淑莹 ^{[1
,2
]}

王冰 ^{[1
]}

机构：

[1] 长春中医药大学吉林省人参科学研究院

[2] 中国科学院长春应用化学研究所

来源：

药学学报 | 2014年 / 05期

关键词：

人参; 皂苷; 适应原; HPA轴; 应激;

D O I：

10.16438/j.0513-4870.2014.05.002

中图分类号：

R285 [中药药理学];

学科分类号：

1008 ;

摘要：

人参是一种典型的适应原,它的作用与下丘脑-垂体-肾上腺系统(HPA)轴内分泌系统有关。皂苷是人参中的主要有效成分,具有与固醇类激素相似的结构。本文结合适应原的定义和HPA轴调节作用的规律,从总皂苷和皂苷单体两方面探讨了人参对HPA轴作用的影响,并总结了其药理作用与HPA轴作用的关系。

引用

页码：569 / 575

页数：7

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