主观皮肤类型与皮肤屏障功能的关系

被引：15

作者：

陶荣

牛悦青

郭建美

仲少敏

吴艳

机构：

[1] 北京大学第一医院皮肤性病科

来源：

临床皮肤科杂志 | 2015年 / 44卷 / 01期

关键词：

油性皮肤; 中性皮肤; 干性皮肤; 皮肤屏障功能;

D O I：

10.16761/j.cnki.1000-4963.2015.01.005

中图分类号：

R751 [皮肤病学];

学科分类号：

摘要：

目的:比较不同主观皮肤类型(油性、中性和干性皮肤)屏障功能指标的差异。方法:利用无创性方法对自评为油性、中性和干性皮肤的20～25岁北京城市女性(各30例)进行皮脂分泌率(SER)、角质层含水量、p H值和经皮肤水分丢失(TEWL)值的检测,并采用胶带连续粘脱后监测TEWL值变化的方法评价角质层完整性,采用角质层取样蛋白定量的方法评价角质层黏合力和丝氨酸蛋白酶活性。结果:主观皮肤类型为中性皮肤者具有最佳的屏障功能;干性皮肤和油性皮肤者面颊部的屏障功能均有不同程度的受损,表现为TEWL值明显升高、p H值升高、丝氨酸蛋白酶活性增加;但二者也有区别,油性皮肤者角质层完整性下降更明显,而干性皮肤主要是角质层黏合力明显减弱。结论:自评为油性和干性皮肤者与中性皮肤者相比,屏障功能均存在一定程度的缺陷,油性皮肤与干性皮肤均具有不同特点,且与其屏障受损的机制不同有关。

引用

页码：3 / 6

页数：4

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