肺纤维化中细胞凋亡及其机制的研究进展

被引:7
作者
李翔
机构
[1] 中南大学湘雅医学院病理学教研室湖南长沙
关键词
肺纤维化; 细胞凋亡; 信号转导;
D O I
暂无
中图分类号
R563 [肺疾病];
学科分类号
1002 ; 100201 ;
摘要
肺纤维化以肺泡上皮细胞凋亡导致肺泡结构破坏和肺成纤维细胞增生为特征。肺细胞凋亡参与肺纤维化的起始和进展过程 ,特别是肺泡上皮细胞凋亡可能是疾病的早期事件 ;Fas/FasL ,Caspase ,p5 3,bcl 2以及其它凋亡调节蛋白参与了肺纤维化的细胞凋亡调节。对肺纤维化发生机制 (尤其是早期阶段 )新的认识 ,为发展新的治疗策略提供了重要信息
引用
收藏
页码:125 / 127
页数:3
相关论文
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