细菌荚膜多糖的化学结构

被引:15
作者
张紫恒 [1 ]
赵峡 [1 ]
于广利 [1 ]
王楷 [2 ]
机构
[1] 中国海洋大学医药学院海洋药物教育部重点实验室山东省糖科学与糖工程重点实验室
[2] 中国动物卫生与流行病学中心
关键词
荚膜多糖; 化学结构; 细菌; 疫苗;
D O I
10.13488/j.smhx.2011.05.026
中图分类号
Q936 [微生物生物化学];
学科分类号
071005 [微生物学];
摘要
荚膜是一些细菌所具有的表层结构,与多种疾病有着密切联系。细菌荚膜多糖不仅结构复杂,而且在免疫活性方面发挥着重要的作用。同一种细菌根据其荚膜多糖的抗原性不同可分为不同的血清型,不同血清型细菌荚膜多糖的化学结构也存在差异。以荚膜多糖为基础的疫苗正在积极研究开发当中,对不同致病细菌荚膜多糖具体化学结构的掌握是疫苗得到许可的必备条件之一。本文对致病细菌荚膜多糖的化学结构进行了归纳和总结,以期为荚膜多糖的化学结构研究和疫苗开发提供参考。
引用
收藏
页码:688 / 696
页数:9
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