Non-HDL-C:血脂干预管理的新靶标

被引:6
作者
陶凌
刘毅
机构
[1] 第四军医大学西京医院心脏内科
关键词
血脂异常; 剩留心血管病风险; 非高密度脂蛋白胆固醇;
D O I
10.13201/j.issn.1001-1439.2013.09.025
中图分类号
R589.2 [脂肪代谢障碍];
学科分类号
摘要
LDL-C被认为是启动及调整降脂治疗的首要目标,如果仅考虑LDL-C水平,可能低估心血管疾病危险。即使强化他汀治疗,仍然存在剩留心血管病风险。非高密度脂蛋白胆固醇(non-HDL-C)是体内总胆固醇减去HDL-C后的剩余部分,能更全面反映包括LDL、IDL及VLDL等"坏血脂"的代谢变化。众多循证医学证据显示,non-HDL-C不仅更有助于预测心血管事件的发生,而且还是更恰当的他汀类药物治疗目标。
引用
收藏
页码:643 / 645
页数:3
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