Tourette’s综合征患者血清脑源性神经营养因子表达水平对照研究

被引：7

作者：

程宇航 ^{[1
]}

何凡 ^{[1
]}

江红卫 ^{[1
]}

杨建宏 ^{[1
]}

郑毅 ^{[1
]}

机构：

[1] 首都医科大学附属北京安定医院

来源：

精神医学杂志 | 2010年 / 04期

基金：

北京市自然科学基金;

关键词：

Tourette’s综合征; 脑源性神经营养因子; 血清;

D O I：

暂无

中图分类号：

R749.94 [儿童精神病];

学科分类号：

100205 ;

摘要：

目的探讨Tourette’s综合征(TS)患者血清脑源性神经营养因子水平。方法用ELISA法检测31例TS患者和29例年龄性别相匹配的正常人血清中BDNF含量。结果 TS组血清BDNF含量显著低于正常对照组[(14.26±10.69)ng/mlvs(23.34±6.86)ng/ml,P=0.001]。结论 BDNF表达的下调可能是导致TS神经退行性改变的细胞分子机制之一。

引用

页码：248 / 249

页数：2

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