环境光对哺乳动物昼夜节律和大脑功能的影响

被引:13
作者
逄文强
张建法
机构
[1] 南京理工大学分子代谢中心
基金
国家自然科学基金重点项目;
关键词
环境光; 睡眠; 生物节律; 大脑认知能力;
D O I
暂无
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
昼夜循环对人类和其他动物的生理和行为有着巨大的影响。光照条件能影响动物的视觉成像,并通过向大脑中的生物钟中心发送信号来调整生理和行为的节律。环境光向生物钟传递信号的系统包含了一个复杂的神经递质复合体-受体-第二信使系统。在夜间曝光能迅速启动下丘脑视交叉上核中大量相关的早期基因。此外,许多白天活动的物种,通常都是在光照条件下获得认知。本文综述了环境光对哺乳动物睡眠、生物节律、大脑认知能力和基因表达等生理和行为方面的影响。
引用
收藏
页码:973 / 982
页数:10
相关论文
共 75 条
[1]  
Neurobiology:bright blue times. Foster RG. Nature . 2005
[2]  
Human and macaque pupil responses driven by melanopsin-containing retinal ganglion cells. Gamlin PD,McDougal DH,Pokorny J, et al. Vision Research . 2007
[3]  
Circadian regulation of sleep in mammals:role of the suprachiasmatic nucleus. Mistlberger RE. Brain Research . 2005
[4]  
Nuclear receptors linking circadian rhythms and cardiometabolic control. Duez H,Staels B. Arteriosclerosis and Thrombosis . 2010
[5]  
Differential induction and localization of mPer1 and mPer2 during advancing and delaying phase shifts. Lily Yan and Rae Silver. European Journal of Neuroscience . 2002
[6]  
Short-wavelength light sensitivity of circadian, pupillary, and visual awareness in humans lacking an outer retina. FH Zaidi,JT Hull,SN Peirson. Current Biology . 2007
[7]  
Intrinsic near 24-h pacemaker period determines limits of circadian entrainment to a weak synchronizer in human. Wright KP. Proceedings of the National Academy of Sciences of the United States of America . 2001
[8]  
High sensitivity of the human circadian melatonin rhythm to resetting by short wavelength light. Lockley SW. The Journal of Clinical Endocrinology . 2003
[9]   Nuclear Receptors Linking Circadian Rhythms and Cardiometabolic Control [J].
Duez, Helene ;
Staels, Bart .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2010, 30 (08) :1529-1534
[10]   Intrinsically photosensitive melanopsin retinal ganglion cell contributions to the pupillary light reflex and circadian rhythm [J].
Markwell, Emma L. ;
Feigl, Beatrix ;
Zele, Andrew J. .
CLINICAL AND EXPERIMENTAL OPTOMETRY, 2010, 93 (03) :137-149