白细胞介素对糖尿病肾病发病机制影响的研究进展

被引：12

作者：

宋昱佳 ^{[1
]}

温玉洁 ^{[2
]}

刘陶文 ^{[2
]}

机构：

[1] 桂林医学院研究生院

[2] 广西壮族自治区南溪山医院

来源：

临床合理用药杂志 | 2017年 / 10卷 / 04期

关键词：

白细胞介素; 糖尿病肾病; 炎性反应; 研究进展;

D O I：

10.15887/j.cnki.13-1389/r.2017.04.100

中图分类号：

R587.2 [糖尿病性昏迷及其他并发症]; R692.9 [其他疾病];

学科分类号：

1002 ; 100201 ; 100210 ;

摘要：

糖尿病肾病(DN)是终末期肾脏疾病的主要原因,其发病机制尚未完全清楚。研究表明DN是一种炎症性疾病,除了受慢性血糖变化的直接影响,还受炎性细胞因子的作用。白细胞介素(IL)作为重要的细胞因子,可参与免疫应答、介导炎性反应,与糖尿病肾病关系密切。本文就IL-17、IL-18、IL-33、IL-9等在DN发病机制中的作用作一综述。

引用

页码：169 / 171

页数：3

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