冠心病患者动脉僵硬度与左心室重构及心功能的相关性

被引：7

作者：

毛雯

张苗苗

吴迪

机构：

[1] 煤炭总医院心脏中心

来源：

中华老年心脑血管病杂志 | 2014年 / 16卷 / 08期

关键词：

冠心病; 动脉硬化; 心室重构; 冠状血管造影术; 血流速度;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

摘要：

目的探讨冠心病患者动脉僵硬度与左心室重构及心功能的相关性。方法选择心内科住院患者480例,根据冠状动脉造影结果分为冠心病组373例及非冠心病组107例,冠心病组根据超声心动图结果分为左心室正常构型组139例及左心室异常构型组234例。各组行肱踝脉搏波传导速度(BaPWV)测定及超声心动图检查,同时在入选的冠心病组患者中选取42例行多普勒组织成像。结果冠心病组BaPWV明显高于非冠心病组(P<0.01)。左心室异常构型组BaPWV明显高于左心室正常构型组[(1689±305)cm/s vs(1508±280)cm/s,P<0.05]。冠心病组BaPWV与室间隔厚度(IVST)、左心室后壁厚度(PWT)、相对室壁厚度(RWT)、左心室质量指数(LVMI)和二尖瓣舒张早期血流速度/二尖瓣环侧壁舒张早期最大运动速度(Ea)呈正相关,与LVEF、Ea、Ea/二尖瓣环侧壁舒张晚期最大运动速度(Aa)呈负相关(P<0.05,P<0.01)。在除外高血压等的影响后,偏相关分析结果显示,BaPWV与IVST、PWT、RWT、LVMI、LVEF、Ea、Ea/Aa、E/Ea仍显著相关(P<0.01)。多元逐步回归分析显示,BaPWV是LVMI及LVEF的独立影响因素。结论 BaPWV是冠心病患者左心室重构及心功能的影响因素。

引用

页码：811 / 814

页数：4

共 10 条

[1]

Electrocardiographic Left Ventricular Hypertrophy and Arterial Stiffness: The Ohasama Study[J] . Daisuke Watabe,Junichiro Hashimoto,Rieko Hatanaka,Tomohiro Hanazawa,Hiromi Ohba,Takayoshi Ohkubo,Masahiro Kikuya,Kazuhito Totsune,Yutaka Imai. &nbspAmerican Journal of Hypertension . 2006 (12)

[2]

ACC/AHA Guidelines for Coronary Angiography: Executive Summary and Recommendations: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Coronary Angiography)[J] . Patrick J. Scanlon,David P. Faxon,Anne-Marie Audet,Blase Carabello,Gregory J. Dehmer,Kim A. Eagle,Ronald D. Legako,Donald F. Leon,John A. Murray,Steven E. Nissen,Carl J. Pepine,Rita M. Watson,James L. Ritchie,Raymond J. Gibbons,Melvin D. Cheitlin,Kim A. Eagle,Timothy

[3] Structural abnormalities and not diastolic dysfunction are the earliest left ventricular changes in hypertension [J].

Palatini, P ;

Visentin, P ;

Mormino, P ;

Mos, L ;

Canali, C ;

Dorigatti, F ;

Berton, G ;

Santonastaso, M ;

Dal Follo, M ;

Cozzutti, E ;

Garavelli, G ;

Pegoraro, F ;

D'Este, D ;

Maraglino, G ;

Zanata, G ;

Biasion, T ;

Bortolazzi, A ;

Graniero, F ;

Milani, L ;

Pessina, AC .

AMERICAN JOURNAL OF HYPERTENSION, 1998, 11 (02) :147-154

[4]

Standardization of M-mode echocardiographic left ventricular anatomic measurments. Devereux R B,Lutas E M,Casale R N,et al. Journal of the American College of Cardiology . 1984

[5]

Relationship bet-ween Arterial Stiffness Assessed by Brachial-Ankle Pulse Wave Velo-city and Coronary Artery Disease Severity Assessed by the SYNTAXScore. Zhaojun Xiong,Cansheng Zhu,Zhenda Zheng,et al. Journal of Atherosclerosis and Thrombosis . 2012

[6]

Relationship between augmentation index and left ventricular diastolic function in healthy women and men. Higashi H,Okayama H,Saito M,et al. American Journal of Hypertension . 2013

[7] Arterial stiffness correlated with cardiac remodelling in patients with chronic kidney disease [J].

Wang, Ming-Cheng ;

Tsai, Wei-Chuan ;

Chen, Ju-Yi ;

Cheng, Meng-Fu ;

Huang, Jeng-Jong .

NEPHROLOGY, 2007, 12 (06) :591-597

[8] 臂踝脉搏波传导速度对女性冠状动脉粥样硬化的预测价值 [J].

马春梅 ;

叶道斌 ;

朱峰 ;

邓笑伟 ;

史丽燕 ;

王春秋 .

中华老年心脑血管病杂志, 2012, 14 (09) :925-927

[9] Predictive Value of Brachial-Ankle Pulse Wave Velocity for Cardiovascular Events [J].

Han, Jung-Yeon ;

Choi, Dong-Hyun ;

Choi, Seo-Won ;

Kim, Bo-Bae ;

Ki, Young-Jae ;

Chung, Joong-Wha ;

Koh, Young-Youp ;

Chang, Kyong-Sig ;

Hong, Soon-Pyo .

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2013, 346 (02) :92-97

[10]

Brain natriuretic peptide as an integrator of cardiovascular stiffening in hypertension[J] . Dimitris Chatzis,Costas Tsioufis,Dimitris Tsiachris,Efstathios Taxiarchou,Spyros Lalos,Zenon Kyriakides,Dimitris Tousoulis,Ioannis Kallikazaros,Christodoulos Stefanadis. &nbspInternational Journal of Cardiology . 2009 (3)

← 1 →