药物性肝损伤的免疫学研究进展

被引:19
作者
周璐
王邦茂
机构
[1] 天津医科大学总医院消化科
关键词
药物性肝损伤; 自身免疫; 细胞色素P450酶系统; 肝炎,自身免疫性;
D O I
暂无
中图分类号
R595.3 [药源性疾病];
学科分类号
100201 [内科学];
摘要
药物性肝损伤(DILI)的发病机制未明,近年来的研究发现,免疫因素在DILI的发病中起重要作用。本文阐述免疫因素参与DILI发病的最新研究成果,探讨免疫因素参与DILI发病的机制,并比较免疫介导的DILI与药物诱发的自身免疫性肝炎的异同。DILI免疫学研究的开展对DILI和自身免疫性肝炎的防治均具有重要意义。
引用
收藏
页码:641 / 643
页数:3
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