黄芩素的抗肿瘤作用及机制的研究进展

被引：22

作者：

毛捷 ^{[1
]}

徐善水 ^{[1
]}

盛莉莉 ^{[2
]}

王宣之 ^{[1
]}

机构：

[1] 皖南医学院弋矶山医院神经外科

[2] 皖南医学院弋矶山医院肿瘤科

来源：

中国临床药理学与治疗学 | 2009年 / 14卷 / 10期

关键词：

黄芩素; 抗肿瘤; 机制;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

摘要：

黄芩作为清热类中药广泛应用于临床,近年来国内外研究表明,黄芩中黄酮成分黄芩素,通过调节花生四烯酸系统的代谢,诱导肿瘤细胞周期停滞,诱导肿瘤细胞凋亡,抑制肿瘤新生血管生成,抗肿瘤侵袭和转移,增强肿瘤细胞对化疗药物的敏感性等机制发挥其抗肿瘤作用。本文对黄芩素抗肿瘤作用的研究现状及机制作一综述,为临床的进一步应用提供理论基础。

引用

页码：1178 / 1182

页数：5

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