贯叶连翘抗抑郁作用机制的研究进展

被引:58
作者
瞿发林
张理义
余海鹰
李宁
机构
[1] 全军心理疾病防治中心解放军医院,全军心理疾病防治中心解放军医院,全军心理疾病防治中心解放军医院,全军心理疾病防治中心解放军医院常州,常州,常州,常州
关键词
D O I
暂无
中图分类号
R285 [中药药理学];
学科分类号
100806 [中药药理学];
摘要
<正> 贯叶连翘(hypericum perforatom L.)为藤黄科金丝桃属植物,多年生草本,全草入药。别名有过路黄、千层楼、小叶金丝桃等,在两方国家又名“st.John's wort”。生于山坡路旁或杂草丛中,北美、欧洲和亚洲均有分布[1]。在我国分布较广,主要分布在陕西、贵州、四川、甘肃、江苏等地[2]。传统中医认为贯叶连翘具有清心明目、调经活血、止血生肌、解毒消炎的功效。现代药理研究表明:贯叶连翘具有抗抑郁、抗病毒、抗菌、镇痛等作用[3]。贯叶连翘在民间已有2400余年的药用历史,在德国用作抗抑郁药也有百余年的历史。近年来,欧、美等国家将其应用在抑郁症治疗方面,取得厂很好的疗效,其浸膏制剂已在德国上市,并占德国抗中、轻度抑郁症药物市场的将近50%[4],贯叶连翘已成为当前全球研究开发的热点草药之一。现就近几年对贯叶连翘的抗抑郁作用的研究综述如下:1 主要活性成分
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页码:80 / 82
页数:3
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