非小细胞肺癌个体化治疗的靶向分子检测

被引:43
作者
刘标
周晓军
机构
[1] 南京大学医学院临床学院/南京军区南京总医院病理科
关键词
肺肿瘤; 腺癌; 分子; 靶向;
D O I
暂无
中图分类号
R734.2 [肺肿瘤];
学科分类号
100117 [系统生物医学];
摘要
<正>非小细胞肺癌(non-small cell lung cancer,NSCLC)的个体化治疗是目前肿瘤研究领域的热点之一。以EGFR体系突变活化和ALK重排为分子学特征的NSCLC对酪氨酸激酶抑制剂(tyrosine kinase inhibitors,TKIs)如吉非替尼(ge-fitinib)、埃洛替尼(erlotinib)以及可卓替尼(crizotinib)有良好的反应性,而EGFR突变和ALK重排也成为筛选TKIs治
引用
收藏
页码:831 / 837
页数:7
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