髌股关节置换术与全膝关节置换术治疗单纯髌股关节骨关节炎的Meta分析

被引：14

作者：

黄群

陈明

董启榕

徐炜

佘昶

王沉栋

机构：

[1] 苏州大学附属第二医院骨科

来源：

中华关节外科杂志(电子版) | 2013年 / 7卷 / 04期

关键词：

骨关节炎,膝; 关节成形术,置换,膝; Meta分析;

D O I：

暂无

中图分类号：

R687.4 [关节手术];

学科分类号：

100220 [骨科学];

摘要：

目的目的比较髌股关节置换术(PFA)与全膝关节置换术(TKA)治疗单纯髌股关节骨关节炎(PFOA)的失败率,评价两种不同治疗选择的疗效差异。方法检索Medline、Embase、CBM数据库,收集单纯髌股关节骨关节炎(PFOA)行PFA或TKA的临床试验,提取数据,采用MetaAnalyst3.13进行Meta分析。结果纳入39个回顾性临床试验,髌股关节置换1599膝,全膝关节置换患267膝。总的PFA组(包括第一代、第二代PFA)失败率13.6%[95%CI(0.103,0.176)];TKA组失败率1.8%[95%CI(0.007,0.044)];第一代PFA假体失败率19%[95%CI(0.143,0.247)];第二代PFA假体失败率8.3%[95%CI(0.053,0.128)]。结论 PFOA患者行PFA的失败率比TKA高,需要再手术或翻修,这与假体设计和适应证的选择有关。第二代PFA假体翻修率与第一代相比明显降低。

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页码：491 / 498

页数：8

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