炎症反应与早产儿脑损伤

被引：2

作者：

戴红梅

罗小平

机构：

[1] 华中科技大学同济医学院附属同济医院儿科

来源：

中华儿科杂志 | 2008年 / 01期

关键词：

D O I：

暂无

中图分类号：

R686 [筋腱、韧带、滑囊疾病及损伤];

学科分类号：

摘要：

<正> 早产是影响新生儿发病率与死亡率最重要的因素,其发生率在美国报道为10%～12%,国内为12.7%～20.8%。早产儿是神经发育受损的高危群体,其脑损伤及随后脑瘫(cerebral palsy,CP)的发生率较足月儿显著增高。早产儿脑损伤主要包括脑室周及脑室内出血(periventricular/intraventrieular hemorrhage,PVH/IVH)、脑白质损伤(whitermatter damage,WMD)尤其是脑室周围白质软化

引用

共 11 条

[1] Role of interleukin-6 in lipopolysaccharide-induced brain injury and behavioral dysfunction in neonatal rats [J].

Pang, Y. ;

Fan, L. -W. ;

Zheng, B. ;

Cai, Z. ;

Rhodes, P. G. .

NEUROSCIENCE, 2006, 141 (02) :745-755

[2]

Differential effects of chemokines on oligodendrocyte precursor proliferation and myelin formation in vitro[J] . Linda Kadi,Ram Selvaraju,Patricia de Lys,Amanda E.I. Proudfoot,Timothy N.C. Wells,Ursula Boschert.Journal of Neuroimmunology . 2006 (1)

[3] Neonatal hypoxia/ischemia is associated with decreased inflammatory mediators after erythropoietin administration [J].

Sun, Y ;

Calvert, JW ;

Zhang, JH .

STROKE, 2005, 36 (08) :1672-1678

[4]

Fetal and neonatal inflammatory response and adverse outcome[J] . L. Cornette.Seminars in Fetal and Neonatal Medicine . 2004 (6)

[5]

Chemokine-dependent mechanisms of leukocyte trafficking across a model of the blood–brain barrier[J] . E.A Eugenin,Joan W Berman.Methods . 2003 (4)

[6]

Endotoxemia Severely Affects Circulation During Normoxia and Asphyxia in Immature Fetal Sheep[J] . Y. Garnier.Journal of the Society for Gynecologic Investigat . 2001 (3)

[7]

Maturation of oligodendrocytes is more sensitive to TNFα than is survival of precursors and immature oligodendrocytes[J] . Wendy Cammer,Hong Zhang.Journal of Neuroimmunology . 1999 (1)

[8]

CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood–brain barrier breakdown[J] . Daniel Anthony,Robert Dempster,Sara Fearn,John Clements,Graham Wells,V.Hugh Perry,Katharine Walker.Current Biology . 1998 (16)

[9]

White matter injury in the preterm infant: an important determination of abnormal neurodevelopment outcome[J] . Jeffrey M Perlman.Early Human Development . 1998 (2)

[10]

The role of tumour necrosis factor, interleukin 6, interferon- γ and inducible nitric oxide synthase in the development and pathology of the nervous system[J] . Progress in Neurobiology . 1998 (3)

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