高速逆流色谱在天然产物分离中的应用——紫杉烷类二萜及二萜生物碱的制备分离

被引:10
作者
饶畅
刘欣
张佩玲
陈未名
方起程
机构
[1] 中国医学科学院药物研究所
[2] 中国医学科学院药物研究所 北京
[3] 北京
关键词
高速逆流色谱; 云南红豆杉; 紫杉烷类二萜及二萜生物碱;
D O I
10.16438/j.0513-4870.1991.07.006
中图分类号
学科分类号
摘要
高速逆流色谱是一种新发展起来的无载体的液液分配色谱技术。它利用聚四氟乙烯(PTFE)螺旋管的方向性与高速行星式运动相结合,产生一种独特的流体动力学现象,使互不相溶的两相溶液在螺旋管中充分混合,顺序传递,导致样品中各个组分由于分配系数的差别而有效的分离。本文介绍了国产的高速逆流色谱仪及应用该仪器制备分离云南红豆杉中结构相近的三种紫杉烷类二萜及二萜生物碱。
引用
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页码:510 / 514
页数:5
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