抑郁症的神经内分泌学初步研究

被引：12

作者：

张宁

侯钢

方群

机构：

[1] 南京医科大学附属脑科医院

来源：

临床精神医学杂志 | 2002年 / 04期

关键词：

抑郁症; β内啡肽; 神经内分泌;

D O I：

暂无

中图分类号：

R749.4 [情感性精神病];

学科分类号：

100205 ;

摘要：

目的 :研究抑郁症的血浆 β 内啡肽及其他神经内分泌改变。　方法 :采用放射免疫法对抑郁症患者的血浆 β 内啡肽及其他神经内分泌进行测定 ,并与正常人对照。　结果 :患者组的 β 内啡肽(β EP)、生长抑素 (SS)、肿瘤坏死因子 (TNF)、白细胞介素 8(IL 8)、白细胞介素 10 (IL 10 )明显高于对照组 ,女性白细胞介素 6 (IL 6 )高于对照组 ,生长激素 (GH)低于对照组。促肾上腺皮质激素 (ACTH)、促肾上腺皮质激素释放激素 (CRH)、催乳素 (PRL)、神经肽Y(NPY)、白细胞介素 1(IL 1)、白细胞介素 2 (IL 2 )、白细胞介素 4 (IL 4 ) ,两组无差异。　结论 :抑郁症存在血浆 β 内啡肽及其他神经内分泌异常。

引用

页码：208 / 209

页数：2

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