新型抗糖尿病药物二肽基肽酶Ⅳ抑制剂

被引：17

作者：

焦伟杰 ^{[1
]}

朱崇泉 ^{[2
]}

赖宜生 ^{[1
]}

张奕华 ^{[1
]}

曹庆先 ^{[2
]}

机构：

[1] 中国药科大学新药研究中心

[2] 江苏省药物研究所

来源：

药学进展 | 2008年 / 07期

关键词：

2型糖尿病; 二肽基肽酶Ⅳ抑制剂; 构效关系;

D O I：

暂无

中图分类号：

R977.1 [激素类药物];

学科分类号：

100710 [药物代谢动力学];

摘要：

2型糖尿病严重威胁着人类健康,而现有抗糖尿病药物不能有效阻止糖尿病患者病情恶化。二肽基肽酶Ⅳ抑制剂作为新型抗糖尿病药物越来越引起人们关注。介绍以二肽基肽酶Ⅳ为靶标的药物研究现状,重点探讨不同类型的二肽基肽酶Ⅳ抑制剂的构效关系。

引用

页码：289 / 296

页数：8

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