性别与胰岛素抵抗

被引:13
作者
徐丹怡
沈建国
机构
[1] 浙江大学医学院附属第一医院内分泌科
关键词
胰岛素抵抗; 糖尿病; 性别;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
胰岛素抵抗(IR)是近年来研究的热点,越来越多的证据表明IR具有显著的性别差异,且女性发生IR的危险性似乎较男性更高。IR的性别差异与脂肪分布、性激素、性别相关的基因表达、血浆游离脂肪酸以及对治疗的反应等多方面因素相关,其发生机制尚不明确,可能主要由性别相关的基因表达及相应代谢调控所决定。
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