限制活动慢性应激大鼠脑组织NO、N0S含量变化的研究

被引：5

作者：

杨来启

吴兴曲

王晓锋

杨喜民

刘光雄

马文涛

张宏宾

李栓德

不详

机构：

[1] 解放军第三医院

[2] 解放军第三医院陕西宝鸡

[3] 陕西宝鸡

来源：

中国临床心理学杂志 | 2002年 / 03期

关键词：

Environmental stress; Limbic system; Nitric oxid; Nitric oxide synthase;

D O I：

10.16128/j.cnki.1005-3611.2002.03.024

中图分类号：

R363 [病理生理学];

学科分类号：

100104 ;

摘要：

Objective: To observe the change in nitric and nitric oxide synthase in limbic system in the rat brain under slow stress. Methods: The slow stress condition was induced by restricted movement of rats, during which the level of NO and activity of NOS were measured in hippocampus, prefrontal and hypothalamus. Results: The level of NO and activity of NOS of hippocampus, hypothalamus and prefrontal in stress group was significantly higher than that in the control group ( P <0.05). Conclusion: The level of NO increased in brain tissues might play a role in stress related disorder.

引用

页码：220 / 221

页数：2