阿魏酸钠减轻对乙酰氨基酚致小鼠肝损

被引:24
作者
汪晖
彭仁琇
机构
[1] 湖北医科大学药理教研室
[2] 湖北医科大学药理教研室 武汉 中国
[3] 武汉
关键词
阿魏酸钠; 对乙酰氨基酚; 谷胱甘肽; 谷胱甘肽转移酶类; 丙二醛; 膜流动性; 肝微粒体; 肝线粒体;
D O I
暂无
中图分类号
R965 [实验药理学];
学科分类号
摘要
小鼠ig阿魏酸钠(100mg·kg-1,qd×10 d)可减轻ip对乙酰氨基酚所致肝损,使血清丙氨酸转氨酶活性下降,肝糖原、谷胱甘肽含量回升,肝脏和肝微粒体谷胱甘肽S-转移酶活性增加,肝丙二醛含量减少以及膜表层流动性降低,说明阿魏酸钠对小鼠肝脏有保护作用。
引用
收藏
页码:82 / 84+101
页数:4
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