高血压病患者血浆脑钠肽水平与左室质量比值的关系

被引:3
作者
张勇
牛云枫
曹中朝
机构
[1] 内蒙古医学院附属医院保健病房
关键词
高血压; 脑钠肽; 左室质量比值; 左室重构;
D O I
暂无
中图分类号
R544.1 [高血压];
学科分类号
100201 [内科学];
摘要
目的:探讨高血压病患者血浆脑钠肽(BNP)水平与左室质量比值(%PLM)的关系,并了解前者在高血压发生、发展过程中的变化。方法:选取61例原发性高血压患者,依据左室质量比值分为左室质量不足组11例,左室质量适宜组(aLVM)29例,左室质量过高(iLVM)组21例。30例同期住院血压正常检查者为对照组。测定血浆脑钠肽含量,行超声心动图检查,计算左室实际质量,左室质量预计值。结果:高血压组与对照组间BNP有显著性差异(P<0.01),且高血压各组间BNP也有显著性差异,以iLVM组最高,左室质量不足组与对照组间BNP无明显差异(P>0.05);BNP与左室质量比值呈正相关(r=0.499),与E/A比值呈负相关(r=-0.262);与LNEF、FS、左房大小、SBP、DBP没有相关性。结论:高血压病时血浆BNP升高,与左室质量比值呈正相关,BNP与高血压左室重构的发生、发展有关并可以作为判断高血压病预后的一项无创生化指标。
引用
收藏
页码:913 / 916
页数:4
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