首发抑郁症患者药物疗效影响因素研究

被引:2
作者
喻妍 [1 ]
赵靖平 [1 ]
杨栋 [2 ]
郭文斌 [3 ]
机构
[1] 中南大学湘雅二医院精神卫生研究所
[2] 湖南省第二人民院
[3] 广西医科大学第一附属医院
关键词
抑郁症; 疗效;
D O I
暂无
中图分类号
R749.4 [情感性精神病];
学科分类号
摘要
目的:探讨抗抑郁药对首发抑郁症患者治疗效果的影响因素。方法:135例首发抑郁症患者接受抗抑郁药治疗6周,比较有效组与无效组的相关因素。结果:有效组与无效组在精神疾病家族史、伴有焦虑症状、自动思维量表(ATQ)总分、汉密尔顿抑郁量表(HAMD)迟滞因子分、简明精神病评定量表(BPRS)焦虑抑郁因子分和总分、明尼苏达多项个性调查表(MMPI)的D分等方面差异有显著性(P<0.05)。Logistic回归分析发现,伴焦虑症状和阳性精神疾病家族史对疗效影响显著(OR=5.651~6.509)。结论:某些因素影响抗抑郁药的疗效,可以作为疗效的预测因素。
引用
收藏
页码:7 / 9
页数:3
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