乳腺癌靶向治疗进展及趋势

被引:3
作者
李会
李兴睿
机构
[1] 华中科技大学同济医学院附属同济医院甲状腺乳腺外科
关键词
乳腺癌; 靶向治疗;
D O I
暂无
中图分类号
R737.9 [乳腺肿瘤];
学科分类号
100214 [肿瘤学];
摘要
<正>乳腺癌是目前中国女性发病率最高的恶性肿瘤,癌症死亡原因位居前列。乳腺癌治疗包括手术治疗、化疗及靶向治疗,其中分子靶向治疗在乳腺癌治疗中至关重要。乳腺癌的靶向治疗经历了内分泌治疗(雌激素受体靶向治疗)、抗人表皮细胞生长因子受体-2(HER2)阳性治疗及免疫相关靶向治疗等几个阶段。
引用
收藏
页码:656 / 659
页数:4
相关论文
共 7 条
[1]
Anti-PD-L1 for metastatic triple-negative breast cancer [J].
Gibson, Josefine .
LANCET ONCOLOGY, 2015, 16 (06) :E264-E264
[2]
Targeting HER2 for the Treatment of Breast Cancer.[J].Mothaffar F. Rimawi;Rachel Schiff;C. Kent Osborne.Annual Review of Medicine.2015, 1
[3]
The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study [J].
Finn, Richard S. ;
Crown, John P. ;
Lang, Istvan ;
Boer, Katalin ;
Bondarenko, Igor M. ;
Kulyk, Sergey O. ;
Ettl, Johannes ;
Patel, Ravindranath ;
Pinter, Tamas ;
Schmidt, Marcus ;
Shparyk, Yaroslav ;
Thummala, Anu R. ;
Voytko, Nataliya L. ;
Fowst, Camilla ;
Huang, Xin ;
Kim, Sindy T. ;
Randolph, Sophia ;
Slamon, Dennis J. .
LANCET ONCOLOGY, 2015, 16 (01) :25-35
[4]
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response [J].
de Azambuja, Evandro ;
Holmes, Andrew P. ;
Piccart-Gebhart, Martine ;
Holmes, Eileen ;
Di Cosimo, Serena ;
Swaby, Ramona F. ;
Untch, Michael ;
Jackisch, Christian ;
Lang, Istvan ;
Smith, Ian ;
Boyle, Frances ;
Xu, Binghe ;
Barrios, Carlos H. ;
Perez, Edith A. ;
Azim, Hatem A., Jr. ;
Kim, Sung-Bae ;
Kuemmel, Sherko ;
Huang, Chiun-Sheng ;
Vuylsteke, Peter ;
Hsieh, Ruey-Kuen ;
Gorbunova, Vera ;
Eniu, Alexandru ;
Dreosti, Lydia ;
Tavartkiladze, Natalia ;
Gelber, Richard D. ;
Eidtmann, Holger ;
Baselga, Jose .
LANCET ONCOLOGY, 2014, 15 (10) :1137-1146
[5]
Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial [J].
Krop, Ian E. ;
Kim, Sung-Bae ;
Gonzalez-Martin, Antonio ;
LoRusso, Patricia M. ;
Ferrero, Jean-Marc ;
Smitt, Melanie ;
Yu, Ron ;
Leung, Abraham C. F. ;
Wildiers, Hans .
LANCET ONCOLOGY, 2014, 15 (07) :689-699
[6]
Safety and Efficacy of Everolimus With Exemestane vs. Exemestane Alone in Elderly Patients With HER2-Negative; Hormone Receptor–Positive Breast Cancer in BOLERO-2.[J].Kathleen I. Pritchard;Howard A. Burris;Yoshinori Ito;Hope S. Rugo;Shaker Dakhil;Gabriel N. Hortobagyi;Mario Campone;Tibor Csöszi;José Baselga;Puttisak Puttawibul;Martine Piccart;Daniel Heng;Shinzaburo Noguchi;Vichien Srimuninnimit;Hugues Bourgeois;Antonio Gonzalez Martin;Karen Osborne;Ashok Panneerselvam;Tetiana Taran;Tarek Sahmoud
[7]
First FDA Approval of Dual Anti-HER2 Regimen: Pertuzumab in Combination with Trastuzumab and Docetaxel for HER2-Positive Metastatic Breast Cancer [J].
Blumenthal, Gideon M. ;
Scher, Nancy S. ;
Cortazar, Patricia ;
Chattopadhyay, Somesh ;
Tang, Shenghui ;
Song, Pengfei ;
Liu, Qi ;
Ringgold, Kimberly ;
Pilaro, Anne M. ;
Tilley, Amy ;
King, Kathryn E. ;
Graham, Laurie ;
Rellahan, Barbara L. ;
Weinberg, Wendy C. ;
Chi, Bo ;
Thomas, Colleen ;
Hughes, Patricia ;
Ibrahim, Amna ;
Justice, Robert ;
Pazdur, Richard .
CLINICAL CANCER RESEARCH, 2013, 19 (18) :4911-4916