重症急性胰腺炎死亡患者的临床特征分析

被引:16
作者
刘晓颖 [1 ]
黄洁 [1 ]
费健 [2 ]
毛恩强 [1 ]
汤耀卿 [1 ]
张圣道 [2 ]
陈尔真 [1 ]
机构
[1] 上海交通大学医学院附属瑞金医院重症医学科
[2] 上海交通大学医学院附属瑞金医院普外科
关键词
重症急性胰腺炎; 死亡; 临床特征;
D O I
暂无
中图分类号
R657.51 [];
学科分类号
摘要
目的分析重症急性胰腺炎(SAP)患者死亡相关的危险因素。方法分析906例SAP患者的临床资料,根据患者的预后分为死亡组和存活组。比较死亡组与存活组患者的年龄、性别、急性生理与慢性健康(APACHE)Ⅱ评分、Ranson评分、CT严重指数(CTSI)、病因、单个或多脏器功能障碍/衰竭、手术、并发症等的差异。结果死亡组患者149例,存活组患者757例。死亡组中,45.0%的患者死于发病14 d内。特发性SAP患者病死率(28.0%)高于胆源性SAP(16.6%)和高脂血症性SAP(5.5%),差异均有统计学意义(均P<0.05)。死亡组多脏器功能障碍/衰竭的发生率(76.5%)显著高于存活组(12.7%)(P<0.05)。在死亡组患者并发症中,严重脓毒血症的发生率(53.0%)最高,且显著高于存活组的23.2%(P<0.05)。死亡组清创手术率高于存活组,但差异无统计学意义(P>0.05)。结论 SAP患者的死亡与高龄、发病原因、多脏器功能障碍/衰竭、严重感染及局部并发症有关;重视个体化的诊断与评估,积极防治并发症和脏器功能损伤是改善预后的关键。
引用
收藏
页码:640 / 643
页数:4
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