2型糖尿病患者颈动脉病变及其大血管并发症危险因素相关性研究

被引:8
作者
荆丹清
尹士男
胡景胜
白桦
机构
[1] 中国人民解放军总医院附属第一医院内分泌科
关键词
2型糖尿病; 大血管病变; 颈动脉内膜中层厚度;
D O I
暂无
中图分类号
R587.2 [糖尿病性昏迷及其他并发症];
学科分类号
1002 ; 100201 ;
摘要
目的:分析2型糖尿病患者颈动脉内膜中层厚度与大血管并发症及危险因素相关性。方法:2型糖尿病伴发大血管病变组141例,2型糖尿病未伴发大血管病变组128例,正常对照组133例,检测其颈动脉内膜中层厚度及斑块,同时测定其血糖、血脂、C肽、体重指数及高敏C反应蛋白(hCRP)水平,比较3组间颈动脉内膜中层厚度及斑块发生率,分析其影响因素。结果:2型糖尿病伴发大血管病变组、2型糖尿病未伴发大血管病变组及正常对照组颈动脉内膜平均厚度分别为(1.09±0.22)mm、(O.89±0.23)mm、(0.66±0.13)mm,组间均有显著性差异(P<0.01);3组中斑块的发生率分别为63.1%、28.91%及0%,均有显著性差异(P<0.05)。在2型糖尿病患者合并大血管病变中,颈动脉内膜中层厚度与hCRP呈正相关(P<0.001)。结论:血清hCRP与2型糖尿病患者颈动脉内膜中层厚度显著相关,hCRP是2型糖尿病大血管病变的显著指标。
引用
收藏
页码:38 / 40
页数:3
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